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Weekly Newsletter - Feb 7
February, 2025
Week 5 of 2025: Jan 27-Feb 2
Read time: under 7 minutes
🚀 Welcome Back, MaxHuman Crew!
This week, we're exposing the silent assassins wrecking your health—and the science-backed ways to fight back. From gut bacteria that build muscle to a pee test that could predict Alzheimer's, it's time to get ahead or get left behind.
No fluff, no BS—just the facts you need to stay ahead of the game.
Let's dive in. 👊🔥
🧬 The Big Hits This Week:
⚡ NAD+: Your body's battery is running out—recharge it or crash.
🧠 Belly Fat & Brain Drain: Your gut size might be suffocating your brain.
🛰 The Sci-Fi Aging Detector: The medical test that predicts your expiration date.
😴 Your Sleep is Lying to You: It's not about time in bed—it's about how you feel.
⚠️Gut Bugs & Diabetes: Sugar isn't just bad—it's turning your microbiome against you.
🧪 Pee Test for Alzheimer's? Your body is leaking clues—are you listening? 🚽🧠🔍
🧬 Your Genes vs. Your Brain: You might be programmed for failure—unless you hack it.
💨 Oxygen & Brain Power: Your brain is suffocating. Fix it before it's too late.
🚱 Kidneys Aging Too Fast? A hidden protein is accelerating the decline.
💊 Brain Supplements That Work: The real deal on nootropics
STUDIES & ARTICLES
1️⃣ NAD+: Your Body's Battery is Dying
Illustration by Yann Valber
Your cells run on NAD+, but aging drains it like a leaky fuel tank. Chronic inflammation speeds up the process, leaving your body exhausted and your brain foggy. This study reveals that eNAMPT and NMN could be the key to keeping your energy up and slowing down aging.
👉 Power Move: Eat anti-inflammatory foods and consider NMN supplements.
Source: npj Aging (2025) | Impact Factor: 8.9
2️⃣ Belly Fat is Killing Your Brain
Your waistline isn't just a vanity issue—it's a death sentence for your brain. Weight-Adjusted Waist Index (WWI) predicts cognitive decline better than BMI, proving that excess belly fat fuels inflammation that eats away at memory and focus.
👉 Fix It: Ditch processed junk, lift weights, and get your gut bacteria in check.
Source: Frontiers in Aging Neuroscience (2025) | Impact Factor: 5.6
3️⃣ The Test That Sees Your Future
Aging could soon be diagnosed like scanning a barcode. Raman Spectroscopy detects molecular shifts in your skin and tissues, spotting oxidative stress, collagen loss, and early aging. This could replace invasive biopsies and outdated medical tests.
👉 What's Next: Get ready for a future where your age is no longer a mystery—science will tell you exactly how much time you have left.
Source: Aging Cell (2025) | Impact Factor: 7.5
4️⃣ Your Sleep is Screwing You Over
Illustration by Benedikt Luft
It's not about how long you sleep. It's about how good it feels. This study proves that subjective sleep quality—how you think you slept—matters more than total hours in bed. Bad sleep equals bad mood, poor focus, and long-term cognitive damage.
👉 Your Fix: Ditch screens, meditate, and set a bedtime routine—like your life depends on it.
Source: Journal of Sleep Research (2025) | Impact Factor: 6.2
5️⃣ Your Gut is Plotting Against You
No news here, but... Sugar-sweetened drinks aren't just rotting your teeth—they're reprogramming your gut bacteria to promote diabetes. This study found that sugar fuels the wrong microbes, triggering insulin resistance and metabolic chaos.
👉 Kill the Sugar: Swap soda for kombucha or simply probiotic-rich foods—your gut will thank you.
Source: Cell Metabolism (2025) | Impact Factor: 31.1
6️⃣ Urine Metabolomics in Alzheimer's Detection
Illustration by Sandro Rybak
Turns out, urine holds clues about Alzheimer's. This study spotted key metabolites—like Theophylline and Vanillylmandelic Acid (VMA)—that could predict who's heading toward cognitive decline. A non-invasive pee test to catch Alzheimer's early? Sounds better than waiting for symptoms to set in.
👉 Key: Expect future non-invasive tests for Alzheimer's detection.
Source: Frontiers in Aging Neuroscience (2025) | Impact Factor: 5.6
7️⃣ Apolipoprotein E and Brain Health
Your ApoE gene is playing a game with your brain. If you've got ApoE4, you're in the fast lane to Alzheimer's. If you've got ApoE2, congrats—you hit the genetic jackpot. This study digs into how ApoE messes with amyloid beta clearance, tau tangles, and inflammation. The twist? Scientists are looking at ways to tweak it.
👉 The Takeaway: Future treatments may involve modifying ApoE functions.
Source: Frontiers in Aging Neuroscience (2025) | Impact Factor: 5.6
8️⃣ Oxygen: Your Brain's Lifeline
Illustration by Genie Espinosa
Your brain needs oxygen, and it's not getting enough. Hypoxic pockets—tiny oxygen-deprived zones—are popping up in aging brains, leading to cognitive decline. The fix? Exercise, social engagement, and mental stimulation all boost oxygen flow. This study says staying active might just keep your brain from suffocating.
👉 Action plan: Stay active to keep your brain oxygenated.
Frontiers in Aging Neuroscience (2025) | Impact Factor: 5.6
9️⃣ The Hidden Kidney Killer
Caveolin-1 (CAV1) is silently speeding up kidney aging by blocking autophagy—the cellular cleanup crew. This study found that knocking out CAV1 restored autophagy and slowed down renal aging. Translation: If we can control this protein, we might just slow down kidney decline.
👉 Why it matters: Kidney health could be improved by targeting CAV1.
Source: Aging Cell (2025) | Impact Factor: 7.5
In partnership with GlycanAge
How Old Is Your Immune System? GlycanAge Knows.
Illustration by Andrei Nicolescu
Want to know if your health routine is actually working? GlycanAge cuts through the guesswork and shows you how well you're aging—for real. By measuring your immune system's biological age, it reveals how your lifestyle choices impact your health. Think of it as your personal age detective, minus the trench coat.
Ready to level up your health? Take control of your aging journey and see the science in action. Plus, we've got an exclusive deal for you—get 10% off with code MAXHUMAN.
Get the Deal🔟 Brain Supplements That Work
Illustration by Sandro Rybak
Ginkgo biloba, curcumin, resveratrol—sounds like a supplement aisle lineup, right? This meta-analysis of randomized controlled trials says these compounds actually improve cognitive function in people with mild cognitive impairment or early Alzheimer's. But don't expect miracles—it takes at least 6 weeks of consistent use to see results.
👉 Make it work for you: Stick with these supplements for at least six weeks for results.
Source: Frontiers in Aging Neuroscience (2025) | Impact Factor: 5.6
HEALTH HACK OF THE WEEK
🔥 Your gut is your muscle's secret weapon.
Strong gut bacteria = stronger muscles, faster metabolism, and sharper thinking. Load up on fermented foods, fiber, and prebiotics. Your gut isn't just about digestion—it's running the whole damn show.
ATTENTION: These aren't your usual clickbait headlines.
We're diving into peer-reviewed, trustworthy research that could genuinely help you live your best life. No hype, no paid media, just the real deal. No lower Impact Factor than 2.5.
Curious about how we choose our sources? You can always check out maxhuman.ai for all the nitty-gritty on our methods.
And that's a wrap! Stay curious, stay sharp. No more excuses. No more waiting.
Catch you next week! 💪🔥
Cheers,
–Max
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